Rosetta-News

[cappy]

und wieder eine CAPS-news ausm journal

CASP8 is just over half way through, and it is proving to be a real challenge to keep up with all of the targets which keep streaming in. We apologize for the work units released earlier this week that caused problems--these were completely unanticipated based on the many similar calculations we have been doing. CASP is stimulating many new ideas for improving structure prediction methodology which we are trying to test out in parallel with completing the casp challenges, hence you may see some non casp work units alongside the casp proteins. Thanks again for your contributions!

dann noch fröhliches weiter knuspern

[cappy]

und eine news

As many of you have likely noticed, our throughput has decreased significantly in the last week. This was due to a couple bad batches that were sent out last week for CASP8 that were not caught by our Ralph tests. The issue was rather insidious in that the tasks would cause some clients to stall and sit idle so we were not immediately aware of the problem. The task names started with "t405". If you have any of these tasks on your client, PLEASE ABORT THEM. These batches have been cancelled. We are currently testing a fix on Ralph and an update will soon be posted. Sorry for any inconvenience.

wenn einer so freundlich wäre das zu übersetzen werd da nicht so schlau draus

[hias]

As many of you have likely noticed, our throughput has decreased significantly in the last week. This was due to a couple bad batches that were sent out last week for CASP8 that were not caught by our Ralph tests. The issue was rather insidious in that the tasks would cause some clients to stall and sit idle so we were not immediately aware of the problem. The task names started with "t405". If you have any of these tasks on your client, PLEASE ABORT THEM. These batches have been cancelled. We are currently testing a fix on Ralph and an update will soon be posted. Sorry for any inconvenience.

Wie viele von euch bemerkt haben ist unser Output in den letzten Wochen merkbar abgefallen. Dies lag an mehreren schlechten batches die für CASP8 ausgesendet wurden und nicht von Ralph getetestet wurden. Das Problem ist ziemlich heimtückisch, denn die Tasks blockierten die Clients oder "idleten" deswegen haben wir nicht sofort das Problem bemerkt. Die Tasknamen starten mit t405. Falls du welche davon hast, bitte abbrechen! Wir testen gerade eine Reperatur bei Ralph und ein Update wird bald rausgebracht werden. Entschuldigung für die unannehmlichkeiten.

Ne ganz flotte und freie Übersetzung...inhalt sollte schon klar sein.

[cappy]

ah vielen dank ich hat da letztens paar wu´s von :X

[cappy]

und auch die Rosetta beta version bekommt mal ein update auf die version 5.98

The rosetta application has been updated to version 5.98. This version includes a bug fix for the stalled client issue.

es wurde das problem behoben das der client einfach stehen blieb, ich selber hatte ein paar solcher wu´s auf meinem quad

[cappy]

und fleißig geht es bei CAPS8 weiter hier eine meldung dazu aus dem journal

As you have probably noticed, many of the CASP8 targets have been quite large proteins. In the last few days, around 5 new targets were released all below 150amino acids--we are very excited about the possibility of predicting these structures very accurately, and expect to see many work units on these proteins in the next several weeks!.

[cappy]

und nach längerer zeit mal wieder was aus dem rosetta journal

we are down to the last week or so of CASP8! one great thing about casp this year is the many new ideas that have come up during the process, and we are all excited to test these ideas systematically once casp is over. so be ready for a flurry of testing of new methods in August--I'm optimistic this will lead to significant improvements in protein structure prediction!

da bin ich ja mal gespannt was da so alles kommt =)

[DO3PSN]

Hört sich ja sehr vielversprechend an, bin auchmal sehr gespannt!

Gruß

Philipp

[cappy]

eine neue minirosetta version ist raus und zwar 1.32

Version 1.32 of minirosetta is now released. This version includes various updates to the graphics application. Minirosetta graphics now look like rosetta++ graphics. Additionally, a linux graphics application is now available.

The minirosetta database is now being packaged and distributed with the application to deal with backwards compatibility.

Please keep in mind that the graphics frame rate may be reduced due to the extra overhead of shared data between the worker application and the graphics application. To increase the frame rate at the cost of cpu cycles, you can set the "Percentage of CPU time used for graphics" R@h project preference to a higher value than the default.

Also keep in mind that there may still be issues with the linux graphics application.

vllt könnte das noch jemand übersetzen *lieb schaut*

[hias]

minitrosetta 1.32 ist nun veröffentlicht. Diese Version beinhaltet verschiedene Updates der grafischen Anwendung. Minirosetta Grafiken schauen nun aus wie rosetta++ Grafiken. Zusätzlich ist nun eine grafische Linux Anwendung vorhanden.

Die minirosetta Datenbank wird nun mit der Anwendung gepackt und verteilt wegen der abwärts Kompatibilität.

Bitte beachten dass die Grafische frame Rate reduziert sein könnte wegen dem extra Overhead von verteilten Daten zwischen der Arbeits Anwendung und der Grafischen Anwendung. Um die Frame Rate auf Kosten der CPU Cycles zu erhöhen, kann man die "Percentage of CPU time used for graphics" erhöhen in der R@h Projekt Einstellung.

Beachtet auch dass es immer noch zu Problemen mit der grafischen Linux Anwendung kommen kann.

[cappy]

endlich wieder eine news ausm journal

CASP8 is now finally over! After the "normal" prediction season, we were sent a new type of challenge--to refine a starting structure model to increase its accuracy and decrease its energy. These refinement challenges occupied us for much of August.

The structures of many of the CASP8 targets have now been made public and we are comparing the predictions made on your computers to the actual structures. There are already some very nice predictions in the set we know the answer for so far!

Those of you who particpated in CASP7 will remember that it is not until the CASP meeting in December that we can compare your results to those of other groups. We of course hope the results will be as good as in previous CASP challenges!

In other rosetta@home news, you will have noticed that David Kim has done an amazing job with the mini-rosetta graphics as it now is as beautiful as the old rosetta graphics was--I hope you are enjoying looking at it.

Our goal for the next months before the CASP meeting is to automate all of the new techniques we developed during casp8 to create an automatic pipeline that can generate protein structure models as accurate as those we generated in CASP8. Needless to say, this will require a very large amount of testing and benchmarking of the new methods and you will see these jobs running on your computers soon!

Thanks again for your contributions during CASP8 and during this next period where we try to push the envelope of protein structure prediction methodology!

[Der Diplomat]

Das Wichtigste übersetzt:
Nach der gewöhnlichen Vorhersage-Runde ging es darum die Start-Struktur-Modelle der Vorhersagen in ihrer Genauigkeit zu verbessern und die benötigte Energie zu verringern.
Die Strukturen der CASP8-Ziele wurden veröffentlicht. Diese werden nun vom Rosetta-Projekt-Team mit den Computer-Vorhersagen verglichen.
Erst nach der CASP8 Tagung, die vom 3. bis 7. Dezember 2008 in der Nähe von Cagliari, Sizilien stattfindet, wird es möglich sein die Ergebnisse mit denen anderer Gruppen (z.B. Poem@Home) zu vergleichen..
Ziel des Rosetta-Projektteams ist es nun die neu entwickelten Techniken zu automatisieren und sie so in Rosetta einzubinden, dass die Herstellung der Protein-Struktur-Modelle in der Genauigkeit des CASP8-Laufs zum Standard werden. Zahlreiche Versuche und weitere Benchmarks der neuen Methoden müssen durchgeführt werden, die in weiteren Arbeitseinheiten auf Euren Rechnern offensichtlich werden.