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Rosetta@home tries to predict protein structures and protein binding. The goal of the project is to develop methods that can safely predict protein structures from amino acid sequences. These methods can help combat diseases such as cancer, HIV or malaria. Rosetta was developed by the University of Washington and is considered the best program for predicting the protein folding, since it has achieved always very good results in the CASP-competition.

Unlike the Human Proteome Folding Project that uses the Rosetta software, Rosetta@home attempts to improve the Rosetta software itself. That is why the project belongs to the category basic research.

A special feature of the project is, that you can set the calculation time of the work unit (wu) in your account. This has no scientific, but an organizational background: with longer WUs the server of the project and the bandwidth of the user are spared. However, each WU does at least one complete convolution simulation before it is terminated. For a randomly complex protein, a WU can run for 6 hours or even longer, even if it has a much shorter runtime. Before changing the so-called "target CPU run time", you should have all open WUs processed and only after the change load new tasks. [1]

Audio-Description Detailed Audio-Description of the project (German): BOINCcast

There is a separate project that tests program versions before they are acquired by Rosetta. It is called: Ralph@home.

In addition to grid computing, the researchers of this project also try to use the concept of Distributed Thinking. To this end, they have developed the foldit game, along with other members of the Computer Science and Engineering and Biochemistry departments of the University of Washington, where the player folds proteins himself.

Project overview

InfoIcon.png Rosetta@home
Name Rosetta@home
Category Biochemie/en
Goal Predicting protein structures
Commercial   nein

United States01.gif    This project is being conducted in Washington, USA.

Project status

InfoIcon.png Project status
Status   active
Begin 16.09.2005
End still active

Project links

Neuigkeiten (RSS-Feed)

Scientific background


Wo Übersicht Top Teams Top User
Projekt Home Page Top Teams Top User Übersicht Top Teams Top User Übersicht Top Teams Top User



Operating systems

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Icon windows 16.png   Windows 64bit Checkbox 1.gif  
Icon linux 16.png   Linux Checkbox 1.gif  
Icon linux 16.png   Linux 64bit Checkbox 1.gif  
Android.jpg   Android Checkbox 1.gif  
Icon dos 16.png   DOS Checkbox 0.gif  
Icon macos 16.png   MacOS X Checkbox 1.gif  
Icon macos 16.png   MacOS X 64bit Checkbox 1.gif  
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Icon java 16.png   Java (OS independent)  Checkbox 0.gif  

Client properties

Funktioniert auch über Proxy Checkbox 0.gif
Normal ausführbares Programm Checkbox 0.gif
Als Bildschirmschoner benutzbar Checkbox 0.gif
Kommandozeilenversion verfügbar Checkbox 0.gif
Personal Proxy für Work units erhältlich   Checkbox 0.gif
Work units auch per Mail austauschbar Checkbox 0.gif
Quellcode verfügbar Checkbox 0.gif
Auch offline nutzbar Checkbox 0.gif
Checkpoints Checkbox 1.gif


Rosetta@home/en benutzt die BOINC-Infrastruktur. Die Anmeldung, Installation und Konfiguration sind auf der allgemeinen BOINC-Seite beschrieben.


  • You can set the running time of the work units on the website. There are settings from one hour to one day. The default is 3 hours. If the error rate is low, a longer duration is recommended.

Published versions

The most recent versions are published here.





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