Rosetta@home/en

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Rosetta@home tries to predict protein structures and protein binding. The goal of the project is to develop methods that can safely predict protein structures from amino acid sequences. These methods can help combat diseases such as cancer, HIV or malaria. Rosetta was developed by the University of Washington and is considered the best program for predicting the protein folding, since it has achieved always very good results in the CASP-competition.

Unlike the Human Proteome Folding Project that uses the Rosetta software, Rosetta@home attempts to improve the Rosetta software itself. That is why the project belongs to the category basic research.

A special feature of the project is, that you can set the calculation time of the work unit (wu) in your account. This has no scientific, but an organizational background: with longer WUs the server of the project and the bandwidth of the user are spared. However, each WU does at least one complete convolution simulation before it is terminated. For a randomly complex protein, a WU can run for 6 hours or even longer, even if it has a much shorter runtime. Before changing the so-called "target CPU run time", you should have all open WUs processed and only after the change load new tasks. [1]

Detailed Audio-Description of the project (German): BOINCcast

There is a separate project that tests program versions before they are acquired by Rosetta. It is called: Ralph@home.

In addition to grid computing, the researchers of this project also try to use the concept of Distributed Thinking. To this end, they have developed the foldit game, along with other members of the Computer Science and Engineering and Biochemistry departments of the University of Washington, where the player folds proteins himself.

Project overview

Rosetta@home
Name	Rosetta@home
Category	Biochemie/en
Goal	Predicting protein structures
Commercial	nein
Homepage	boinc.bakerlab.org/rosetta


	This project is being conducted in Washington, USA.

Project status

Project status
Status	active
Begin	16.09.2005
End	still active

Project links

Neuigkeiten (RSS-Feed)

e-Library (RKN-Wiki)

Scientific background

Statistics

Wo	Übersicht	Top Teams	Top User
Projekt Home Page		Top Teams	Top User
BOINCstats.com	Übersicht	Top Teams	Top User
stats.free-dc.org	Übersicht	Top Teams	Top User

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Clients

Operating systems

	Windows
	Windows 64bit
	Linux
	Linux 64bit
	Android
	DOS
	MacOS X
	MacOS X 64bit
	BSD
	Solaris
	Java (OS independent)

Client properties

Funktioniert auch über Proxy
Normal ausführbares Programm
Als Bildschirmschoner benutzbar
Kommandozeilenversion verfügbar
Personal Proxy für Work units erhältlich
Work units auch per Mail austauschbar
Quellcode verfügbar
Auch offline nutzbar
Checkpoints

Configuration

Rosetta@home/en benutzt die BOINC-Infrastruktur. Die Anmeldung, Installation und Konfiguration sind auf der allgemeinen BOINC-Seite beschrieben.

Peculiarities

You can set the running time of the work units on the website. There are settings from one hour to one day. The default is 3 hours. If the error rate is low, a longer duration is recommended.